Water for injection

WFI

Complies with the most stringent regulations

WFI is used for extremely sensitive applications: solution or dilution of substances and preparations for parenteral administration, bulk for the manufacture of parenteral or ophthalmic products, shaping or final rinsing of containers such as primary packaging.

Used in large quantities, it is produced on site by membrane filtration (ultrafiltration, etc.) or distillation. Wherever it is used, its quality is subject to strict controls at the heart of the process, and must comply precisely with the specifications and requirements of the various pharmacopoeias.

 

Cold or thermal, controlled production

By distillation or membrane technology, the production of WFI is dedicated to impeccable quality (absence of contaminants or suspended particles, etc.). Distillation remains the method of choice for many operators, and is essential for producing pure steam.

Membrane technologies, on the other hand, enable cold WFI to be produced, with a membrane barrier for maximum safety. These technologies also consume less energy, offering manufacturers savings and greater profitability.

At BWT we support you

Cold or distilled WFI

For impeccable quality, the tailor-made solution depends on a number of parameters - qualification of quantities and temperatures of use, on-site situation and utility costs.

BWT will work with you to define the best options for your site. Whatever the process chosen, we design, manufacture and install safe systems with a tailored service throughout the lifecycle.

Discover our dedicated support for Pharma & Biotech

Go to the BWT Pharma & Biotech website
bwt multistill

MULTISTILL

The production of water for injection by distillation

bwt osmotron wfi

OSMOTRON WFI

WFI water production using membrane technology

bwt combitron

COMBITRON

The perfect combination for the production of WFI and pure steam.

bwt multitron

MULTITRON

Multi-column distillation using the natural circulation process.

bwt loopo wfi

LOOPO WFI

Safe storage and distribution of water for injection at room temperature.

The BWT AQA Confiance service

The 360° life cycle

To ensure that your installations run smoothly, BWT offers a complete range of services for all its equipment and products, from qualification and validation of requirements and studies to team training, in a spirit of partnership.
AQA CONFIDENCE meets specific needs:

  • Customised maintenance plan
  • Modular and flexible solution
  • Compatible with third-party solutions
  • All services from a single source
  • Ideal preparation for audits and inspections
  • Maximum long-term availability
Download the BWT AQA Confidence brochure

9 pages, langue french, PDF (3.15 MB)

contrats aqa confiance

BWT Aqu@Sense MB innovation

A culture of innovation

Innovation is a real priority for BWT, and one of its main aims is to improve safety and industrial performance.
Our innovation department and integrated design offices develop new technologies, equipment and cutting-edge products for industrial water treatment.

BWT Aqu@Sense MB is a reliable, proven and accurate system for spot or continuous measurement of TCC (Total Cell Count), using flow cytometry technology.

With BWT Aqu@Sense MB the quality of purified water and water for injection (WFI) is perfectly controlled and systematically demonstrable at all times.

Discover our innovative solution
Aquasense produit innovant 3

Our news

The latest news from BWT Industrie

Bannière CFIA Rennes

NEWS - CFIA Rennes trade fair

From 4 to 6 March 2025, come and discover BWT's innovative solutions to optimise your water and energy consumption, reduce your costs and contribute to a more sustainable future!

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document sanofi

DOCUMENTATION - SANOFI Article / INSA / BWT: Aqu@sense MB trial

In this document, find out how our customer was able to better understand the evolution of the microbial load of its water and how our technology was tested by their laboratory. A joint initiative by teams from Sanofi, INSA Toulouse, BWT France and BWT Pharma&Biotech.

Download the document
pharmacopee

BLOG - The European Pharmacopoeia opens up to membrane technologies

Since 1 April 2017, the European Pharmacopoeia has authorised the use of membrane technology to produce water for injection (WFI). This alternative to distillation is based on a cold treatment process that offers the same guarantees in terms of microbiological safety...

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pharmaceutique

BLOG - Continuous monitoring of microbial water quality used for pharmaceutical purposes

Water used in pharmaceutics must be regularly tested for microbial load. Pharmacopoeias recognise the limitations of conventional control methods and recommend the use of other procedures to determine microbial quality. Cutting-edge technologies such as flow cytometry...

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